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Sildenafil vs Avanafil vs Tadalafil vs Vardenafil

Using medicine to treat Erectile Dysfunction

Although there are many different ways to treat the underlying issues that can cause erectile dysfunction (ED), this article will focus on the medicine aspects of dealing with this condition. By all means, we encourage you to explore natural ways to deal with this issue, before engaging into a drug-based therapy. The reality is that using drugs to treat ED is much easier, regardless of the fact that it doesn't solve the issue in the long-term, so we have created this article to help you discover the relevant information you need about ED medicines specifically, what is available on the market, what are the differences and similarities between the various options, and what you can do to make sure that your experience with these drugs will be safe and pleasant.

Market availability

When talking about treating ED with the help of medicine, there are multiple options to consider, as this issue is so popular, that pharmaceutical companies are competing to come up with the best solutions, which often leads to the discovery of new substances capable of achieving this result.
For starters let's have a look at the most common substances and brand names that contain them:

Avanafil (Stendra)
Sildenafil (Viagra)
Tadalafil (Cialis)
Vardenafil (Levitra, Staxyn)


One word of caution, these substances work by enabling a better circulation through relaxation of the muscles in your body. Avanafil, Sildenafil, Tadalafil and Vardenafil can have dangerous interactions with other drugs, especially nitrates, commonly found in angina medicine. This is a condition that occurs when the heart isn't getting enough blood flow, and usually causes chest pains for the individuals. If you are using a nitrate based product to resolve chest pains, make sure to avoid these products as there is a high risk of a dangerous interaction that will cause incredibly low blood pressure, often leading to unconsciousness of the individual.

These substances are all inherently extremely similar to one another, often differentiating in parameters such as, the onset and the length of the effects. Other than these elements, everything else is equivalent. Let's have a look at them, so you can get a better understanding.

Staxyn and Levitra vardenafil, take about 15 minutes to start working after ingestion.
Sildenafil requires about 30 minutes before the effects can be felt.
Stendra's avanafil effects can be felt in about 15 minutes, similar to Staxyn and Levitra vardenafils.
Last but not least, tadalafil takes anywhere between 15-30 minutes to start working.
All of these drugs last up to 5 hours, with the exception of Cialis tadalafil which can last up to 36 hours. Keep in mind that these medicines do not cause an erection that simply will not stop, but instead they work by relaxing the muscles in your body, making it easier to have an erection.

You can easily switch between these solutions as they are compatible with one another and will not cause any sort of discomfort for you. This is perfect, since every body is different and will interact with the drugs in a slightly different manner. Usually what happens is that people experiment with all of them before they decide that they like one of the solutions more than the others.

With this being said, there are some precautions that you need to consider when using any one of these ED medicines. As we mentioned before, nitrates are a big no-no in combination with any of these medicines. There are some other possibly dangerous interactions, and for this reason it is preferable to speak to a doctor about your issue. Don’t be shy or afraid to do so, as ED is a natural and common issue in the life of a modern man.

Your doctor will want to know about your medical history (which they should have on hand, especially if you are regular with your visits), as well as any supplements or nonprescription medication that you may be taking. These drugs can sometimes cause complications, so make sure to follow the directions on the label. Taking this route should be one of the last options, after you have exhausted all natural treatment plans, such as lifestyle change, meditation, or even exercise. Any one of these activities can help you overcome this issue eventually, and having a supportive partner can really help along the way.

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